

The group has also done gaming live-streams for charity, hosting "The Runaway Guys Colosseum" stream for the non-profit organization Direct Relief. The event has been broadcast on numerous gaming conventions such as PAX, Magfest and Momocon. In addition to their videos, The Runaway Guys have also created the "Thrown Controllers" event, a live game show which focuses on video game trivia and challenges. The group records themselves playing various multiplayer video games such as New Super Mario Bros.

The Runaway Guys is a collaborative Let’s Play channel formed by Rosales-Birou, Proton Jon and NintendoCapriSun. His videos have also been described as nostalgic and reflective, as he often tells personal anecdotes of his experiences with the games he plays. In spite of their informative nature, Rosales-Birou’s videos often employ humorous moments in his gameplay, such as the occasional failure or death in a level and subsequent backtracking. In this regard, his gameplay videos function as informative walkthroughs with the premise of guiding players through each aspect of the specific game he plays Ryan Rigney from Wired magazine noted that Rosales-Birou "possesses a near encyclopedic knowledge about the games he’s playing, and reliably dispenses gobs of obscure information as he plays."
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For example, in his Pokémon Emerald series he discusses various strategies and viable techniques to ensure optimal success in the game, and in his second EarthBound series he showcased a particular glitch in the game involving the Tent located in Threed, one of the cities featured in the game. Rosales-Birou commentates in an informative manner in his videos with the purpose of guiding viewers to complete the game themselves. During his gameplay videos, Rosales-Birou attempts to show every aspect of each individual game he plays to 100% completion, including every item, boss battle, sidequest, and Easter egg possible. Contrasting from other Let’s Play channels, his content focuses on footage from Nintendo games several years after their initial release dates, mainly of titles he has played numerous times before.

Rosales-Birou’s gaming videos have been categorized under the walkthrough genre, and have been described as both entertaining and informative. He had previously expressed interest in remaking the series, feeling that he "could have done such a better job now." However, in June 2021, several of Rosales-Birou’s EarthBound videos were content ID-claimed and subsequently blocked worldwide by Sony, due to the company owning the distribution rights to the soundtrack of the Mother series. In 2018, Rosales-Birou remade his EarthBound Let's Play series on the tenth anniversary of his YouTube channel’s formation, going into detail on previously undiscussed trivia and knowledge surrounding the game. On his primary YouTube channel, Rosales-Birou has produced over 40 solo Let's Play series of games primarily exclusive to Nintendo systems, such as EarthBound, Paper Mario: The Thousand Year Door, Pikmin, Super Luigi Galaxy, The Legend of Zelda: Majora’s Mask, Pokémon Emerald, Super Paper Mario, Super Mario 64 DS, Animal Crossing: New Leaf, Xenoblade Chronicles, and Splatoon. Nintendo had initially targeted and content ID-claimed several of Rosales-Birou's videos due to them containing footage of their games, causing his ad revenue to temporarily decrease, but later ceased doing so. Rosales-Birou's channel grew in popularity as his gameplay videos were often recommended on YouTube's suggestions, and he has since become a Let’s Play creator on YouTube as a full-time job in 2014 The Atlantic cited Rosales-Birou as an example of a Let's Player making a living off of gaming videos. Shortly after the incident, he obtained a YouTube partnership with The Game Station (now called Polaris), a sub-network of Maker Studios. In July 2010, Rosales-Birou's YouTube account was suspended under false copyright claims, though was restored in August. On March 26, 2008, he uploaded his first Let’s Play series covering the SNES role-playing game EarthBound on YouTube, adding commentary on the game's sound and art design.

He was initially inspired to make Let's Plays by personalities such as Jonathan "Proton Jon" Wheeler, a Let’s Player originating from the Something Awful forums and a future founding member of The Runaway Guys. Rosales-Birou created his YouTube account on Junder the alias of "Chuggaaconroy," a name he has used as an online pseudonym since he was a child.
